Can I use niacinamide with vitamin C?

Yes. The old myth about niacinamide neutralizing vitamin C was based on 1960s data using pure niacin and heat. Modern formulations layer them safely.

How often can I use niacinamide?

Twice daily is well tolerated by most skin types.

Niacinamide: the multitasker that fits into any routine

Niacinamide is one of the safest, most-studied skincare ingredients available. It calms the skin, evens tone, and improves the barrier without irritation.

What is Niacinamide?

Niacinamide is the amide form of vitamin B3, water-soluble, and stable at a wide range of pH. It is one of the few actives that can be layered with almost anything without breaking down.

How Niacinamide works

Niacinamide boosts the production of ceramides in the skin, which strengthens the barrier and reduces water loss. It also inhibits the transfer of melanin to the surface skin cells, which lightens hyperpigmentation over eight to twelve weeks. Ten percent formulations have been shown to reduce sebum production in oily skin.

Best for

· Redness and rosacea
· Enlarged pores
· Post-inflammatory hyperpigmentation
· Oily skin
· Weak barrier

Pairs with

· Retinol
· Vitamin C
· Hyaluronic acid
· AHAs
· BHAs

Side effects and safety

Rarely causes irritation. High concentrations above ten percent may cause flushing in sensitive skin.

Products worth trying

The Ordinary

Niacinamide 10% + Zinc 1%

Cult favorite, oily skin sebum control

Good Molecules

Discoloration Correcting Serum

Combines niacinamide with tranexamic acid for pigmentation

SkinCeuticals

SkinCeuticals Metacell Renewal B3

Five percent niacinamide plus tightening actives

This article is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting new treatments, supplements, or procedures. Links to products may be affiliate links. Smart Milky may earn a commission at no additional cost to you.